Brendan Steele carded a two-under-par 70 to take a three-shot lead before the Valero Texas Open was suspended due to darkness.
Steele, who is on 10-under, is followed by the trio of Stuart Appleby, Scott Langley and Charley Hoffman as they are on seven-under.
A plethora of golfers are in a tie for fifth on six-under, including Patrick Reed and South Korea’s Sung Kang, who surged up 32 spots on the leaderboard after firing a five-under-par 67.
Meanwhile, defending champion Jimmy Walker missed the cut after recording a disappointing five-over-par 77.
Steele only got through 13 holes on Thursday and went on to register an eight-under-par 64. He then began his second round with a hat-trick of birdies from the second to fourth before faltering with a bogey at the fifth. He atoned for his mistake with a 29-foot birdie putt at the eighth, but stumbled once again with his second bogey of the round at the ninth.
The 33-year-old had a much more turbulent back nine as he made two birdies and a double bogey at the par-four 15th.
Appleby also carded a 70, but his round started in disastrous circumstances as he missed a number of simple putts to register a triple bogey at the par-four 10th. He continued to struggle for consistency on the front nine as he went on to make three birdies and two bogeys.
The Australian shifted his game to a whole new level on the back nine though, as he made four birdies to keep himself three strokes behind Steele.
Langley, who fired a four-under-par 68, was in brilliant form with the putter on the front nine as he made a 16-foot birdie putt at the third, which was followed up with an 18-foot birdie putt at the fourth.
Langley continued his good run of form with a 32-foot chip-in eagle at the par-five 14th before recording a bogey at the next hole. He did manage to finish on a bright note though, as he made his third birdie of the round at the 17th.
Hoffman began his round of 71 with a bogey at the first, but he found his groove after and proceeded to make a trio of birdies, which included a 30-foot putt at the 13th. The 39-year-old had a much tougher time on his back nine as he made three bogeys, but he did manage to make an eagle at the par-five second.
Meanwhile, Walker failed in his bid to retain his title as he made two birdies, three bogeys and two double bogeys during his round of 77.
The Dutchman finished third and second in the first two weeks of the home-based competition.
NFL stars Tom Brady and Peyton Manning will also be involved.
The US President was among the viewers watching the TaylorMade Driving Relief.
The US President phoned in as McIlroy played in a Sunday fundraiser for coronavirus victims.
Syme donated his prize money to charity.
‘This is the life of a caddie…’
The Northern Irishman is ranked number one in the world.
Players entering the United States will face a 14-day quarantine period, while a strict testing regime will be in place at each tournament.
The experienced duo will be involved at Whistling Straits.
The world number 98 intends to split the 10,000 euros prize money between his own charity and a hospital in his native Rotterdam.