Sei Young Kim carded a six-under-par 66 to take a two-shot lead at the JTBC Founders Cup on Friday.
Kim, who is on a tournament-record 15-under 129, is followed by Brittany Lang, who is on 13-under and is in second place on the leaderboard.
Jacqui Concolino and Giulia Sergas are in a tie for third on 12-under, while world number one Lydia Ko surged up the leaderboard and is eight strokes off the lead in a tie for 25th.
Meanwhile, Inbee Park failed to make the cut by one stroke despite firing a three-under-par 69.
Kim, who hit a career-best 63 on Thursday, enjoyed a lot of success during the second round as she made two eagles. The first came at the par-five second, where she sunk a spectacular 30-foot putt, while the second was at the par-five 15th, where she converted a seven-foot putt. The 23-year-old also made three birdies and a bogey during her excellent round.
Lang, who fired a four-under-par 68, was unable to continue her bogey-free run as she made committed her one and only blemish at the seventh. However, Lang atoned for her mistake with five birdies, which saw her maintain her position in second place.
Concolino climbed up 21 spots on the leaderboard after registering an eight-under-par 64, during which she made nine birdies, including three in a row from the 15th to 17th, and a bogey.
Sergas continued to impress during her round of 68 on Friday as she made four birdies, two bogeys and an eagle at the par-five 15th.
After recording a 70 in the first round, Ko shot up the leaderboard as she hit a five-under-par 67. The world number one did not have the best of front nines as she made two birdies and a bogey, but she shifted her game to the next level on her back nine as she made four birdies.
Park meanwhile enjoyed a fairly successful round as she made four birdies and a bogey, but it was not enough to save the world number two from being cut.
The US President was among the viewers watching the TaylorMade Driving Relief.
The US President phoned in as McIlroy played in a Sunday fundraiser for coronavirus victims.
Syme donated his prize money to charity.
‘This is the life of a caddie…’
The Northern Irishman is ranked number one in the world.
Players entering the United States will face a 14-day quarantine period, while a strict testing regime will be in place at each tournament.
The experienced duo will be involved at Whistling Straits.
The world number 98 intends to split the 10,000 euros prize money between his own charity and a hospital in his native Rotterdam.
The biennial event between Europe and the United States is scheduled to take place from September 25-27.